Denuril Injection is a medicine used in the treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures. It makes the bones strong and reduce the risk of fractures.
Denuril Injection is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better. To make it more effective, take adequate amount of calcium and vitamin D supplements while on treatment with this medicine.
Some common side effects of this medicine include pain in extremity, musculoskeletal pain, nerve pain, urinary tract infection, constipation, and rash. Communicate to your doctor if any of these side effects does not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.
To make sure the medicine is safe for you, before taking it, let your doctor know of all the other medicines you are taking. It is important for pregnant and breastfeeding mothers to ask the advice of their doctors before using this medicine.
Your doctor or nurse will give you this medicine. Compassionately do not self administer.
Side Effects:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Ordinary side effects of Denuril
Musculoskeletal (bone, muscle or joint) pain
Pain in extremities
Nerve pain
Constipation
Rash
Urinary tract infection
Warning & Precautions:
Alcohol
CAUTION
Caution is advised when consuming alcohol with Denuril Injection. Please consult your doctor.
Pregnancy
UNSAFE
Denuril Injection is highly unsafe to use during pregnancy. Perceivek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
SAFE IF PRESCRIBED
Denuril Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Denuril Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Denuril Injection is safe to use in patients with kidney disease. No dose adjustment of Denuril Injection is recommended.
Liver
SAFE IF PRESCRIBED
Denuril Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Denuril Injection may not be needed in these patients. Please consult your doctor.
FAQs:
Q. How long can you stay on Denuril Injection?
There is no optimal duration of treatment of osteoporosis with Denuril Injection. The patient’s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Denuril Injection. Depending on this, the duration of taking Denuril Injection is decided.
Q. Does Denuril Injection cause hair loss?
Affirmative, hair loss is a common side effect of Denuril Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.
Q. Is Denuril Injection a chemotherapy drug?
Denuril Injection is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Denuril Injection makes the bones stronger and less likely to break.
Q. How is Denuril Injection given and how often?
Denuril Injection is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Denuril Injection.
Q. Can Denuril Injection be taken during pregnancy?
No, pregnant women should not take Denuril Injection. You must use an effective method of birth control during and for at least 5 months after the last dose of Denuril Injection if you can become pregnant.
Q. How should Denuril Injection be stored?
Denuril Injection should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.
Q. Does Denuril Injection cause osteonecrosis of the jaw?
Osteonecrosis is a rare side effect of Denuril Injection. It refers to the damage caused to the bone of jaw. To avoid this, you should maintain good oral hygiene and receive routine dental check ups while taking Denuril Injection. Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, discharge, pain or swelling, or non-healing of sores. These could be signs of osteonecrosis of jaw.
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